Channelrhodopsins are light-gated ion channels that exist naturally in microalgae. hChR2 is a humanized version of ChR2 for mammalian expression. It is maximally excited by 470 nm light. The wild-type, as well as a few mutations, provide the fastest excitation of the channelrhodopsins offered, and are widely used in optogenetics techniques in neuroscience. Due to delayed channel closure, hChR2(H134R) is a gain-of-function mutation that produces larger photocurrents than wild-type hChR2, but slows down channel kinetics.
Gene/Insert name：hChR2(H134R)
Tag/Fusion protein：EYFP
Titer：>1x10^13 VG/mL，>2x10^12 VG/mL
Volume：100μL
[Right-click on the plasmid map to view the high-resolution image in a new label page.]
