BC-2074 rAAV-TRPV1-hChR2(H134R)-EYFP

Time:2024-08-22 11:45:30
BC-2074  rAAV-TRPV1-hChR2(H134R)-EYFP
Features:This AAV expresses hChR2(H134R)-EYFP driven by Transient receptor potential vanilloid 1 promoter. Source PMID: 25797803

Channelrhodopsins are light-gated ion channels that exist naturally in microalgae. hChR2 is a humanized version of ChR2 for mammalian expression. It is maximally excited by 470 nm light. The wild-type, as well as a few mutations, provide the fastest excitation of the channelrhodopsins offered, and are widely used in optogenetics techniques in neuroscience. Due to delayed channel closure, hChR2(H134R) is a gain-of-function mutation that produces larger photocurrents than wild-type hChR2, but slows down channel kinetics.
Gene/Insert name:hChR2(H134R)
Tag/Fusion protein:EYFP
Titer:>1x10^13 VG/mL,>2x10^12 VG/mL
Volume:100μL

[Right-click on the plasmid map to view the high-resolution image in a new label page.]