Pioneering Innovation in Gene Vector Research

E-mail：BD@ebraincase.com

Tel：+8618971215294

neuroscience viral vectors, optogenetics, chemogenetics, neurotransmitter sensors, GCaMP, neural circuit research, AAV vectors

Fluorescent “superheroes”！ mBaoJin + mScarlet3-H (also known as mYongHong) Tool Viruses Empower Super-Resolution and High-Efficiency Imaging

New Products Discover Latest Neuroscience Viral Tools & Sensors

Precision Gene Delivery to Brain Blood Vessels: A New Tool for Studying Cerebrovascular Diseases—rAAV-miniBEND

The world’s first red fluorescent potassium sensors, RGEPO1/2, are here!

A New Tool for Visualizing α-Syn Aggregates in Live Brains—α-Syn-6H-EGFP/tdT sensor Experiment Guide

Breakthrough | WESTLAKE UNIVERSITY TEAM DEVELOPS HIGH-PERFORMANCE RED GENETICALLY ENCODED CALCIUM PROBE“SOMAFRCAMP!”WITH SENSITIVITY MATCHING TO GCAMP!

Client Publication | Neuron | Collaborative Discovery by Dr. Juan Song’s Team at UNC Reveals Distinct Circuit Targets for Cognitive and Emotional Deficits in Alzheimer’s Disease

Pioneering Innovation in Gene Vector Research

With a focus on advanced neuroscience, we provide advanced technology platforms
to lead the innovation of viral tools for medical research.

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Pre-made AAV Library

Brain Case provides a variety of vector tools, including AAV, lentivirus, rabies virus, and herpes simplex virus, for gene regulation, gene editing, as well as in vitro and in vivo experiments.

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New Research Tools

The toolkits you’ve been looking for, presented by Brain Case

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Support

Brain Case shares the scientific achievements of product users and provides practical techniques and tips.

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What customers say about Brain Case

News

In vivo testing results of retrograde multi-synaptic tracing virus - Pseudorabies Virus (PRV)

Explore in vivo testing of PRV801 for retrograde tracing in mice. Results show strong fluorescence signals in brain regions, highlighting its suitability for CNS studies.

Brain Case Rainbow Combo Program | Flexible Multi-Virus Solutions

Explore the Brain Case Rainbow Flexible Combo Program for flexible multi-virus ordering in neuroscience research. Freely combine optogenetics, chemogenetics, calcium imaging, and neurotransmitter sensor tools with optimized cost efficiency.

Exclusive Membership Program Now Available

Join the Brain Case Membership Program. Enjoy better pricing on in-stock AAVs, custom packaging discounts, priority scheduling, and expert consultations.

Featured Content

Brain Case IP Policy

Brain Case IP Policy Service Nature and Ownership of Intellectual Property Brain Case operates as a contract research and manufacturing service provider specializing in gene delivery systems and viral vector engineering. We manufacture vectors strictly ba

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Cre-loxP & Flp-FRT system | Everything you want to know about recombinase is here

What are Cre and loxP? In 1981, Nat Sternberg et al. reported a protein cloned from the P1 bacteriophage of Escherichia colia 38 kDa recombinase encoded by 343 amino acids called Cre (Cyclization Recombination Enzyme). It specifically recognizes loxP site

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miniDREADD Enables Single-AAV Bidirectional Control

miniDREADD is a compact chemogenetic tool that preserves the functionality of conventional DREADDs while reducing vector size. Compatible with single AAV delivery, it enables efficient bidirectional regulation of neuronal activity in rodents and non-human

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Tool Viruses: The "Delivery Couriers" Tamed by Science

Learn how viral vectors work, including AAV and lentivirus systems, their structures, packaging strategies, and applications in gene therapy, neuroscience, and cell therapy.

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Customer Article | Neuron | Neural Code of Social Avoidance: Hai-Tao Wu’s Team Reveals a New Mechan

Chronic stress, Social behavior, Social fear, Social novelty preference, Anterior insula, Prefrontal cortex, AID→FrA, AIV→PrL, PV interneurons, Oxytocin receptor, Mouse model, CES

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Nature Methods | PinkyCaMP: The Brightest, Non-Photoswitchable Red Calcium Indicator Yet!

PinkyCaMP, an mScarlet-based red GECI, offers high brightness, photostability, and multicolor compatibility for in vitro, ex vivo, and in vivo neural imaging.

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Zhi Zhang’s team at USTC provides a detailed analysis of the core regulatory circuit in Science

This study revealing for the first time the neural circuit mechanisms by which the hypothalamic master clock regulates the circadian rhythm of chronic pain.

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Nature Methods | CaBLAM: A Novel Long-Term Bioluminescent Calcium Indicator Without Excitation Light

CaBLAM is ideal for long-term monitoring of neuronal activity (e.g., learning and memory), imaging in freely behaving animals, and photosensitive samples.

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Visceral Pain in Pancreatitis: Ting Xu's Team at Sun Yat-sen University Reveals a Novel Brain-Pancr

This study identifies a vagus nerve-mediated pancreas-brain pathway (pancreas→NGTRPV1→NTSGlu→PVNGlu) that transmits visceral pain in acute pancreatitis.

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Nature Reviews Neurosci: A Summary of Astrocyte-Specific Targeting and Manipulation Tools!

Explore how tools like DREADDs, LiGluR, and Channelrhodopsin are advancing astrocyte calcium signaling research and its impact on neuroglial interactions and behavior.

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Tel： +8618971215294

E-mail： BD@ebraincase.com