With a focus on advanced neuroscience, we provide advanced technology platforms to lead the innovation of viral tools for medical research.
Brain Case provides a variety of vector tools, including AAV, lentivirus, rabies virus, and herpes simplex virus, for gene regulation, gene editing, as well as in vitro and in vivo experiments.
The toolkits you’ve been looking for, presented by Brain Case
Brain Case shares the scientific achievements of product users and provides practical techniques and tips.
rAAV-miniBEND: Gene delivery to brain endothelial cells and modeling of vascular malformation diseases.
Enjoy up to 35% OFF on viral vectors! Global delivery & fast turnaround from Brain Case Biotech. Promotion ends Nov 9, 2025.
Holiday research sale featuring AAVs, PRV/HSV/RV/VSV tools, combo packs, mystery boxes, and custom virus packaging discounts. Nov 24–Dec 7.
Fudan University’s latest research uncovers a crucial neural circuit (PC → Lent → DG) responsible for driving epileptic seizures and brain-wide functional reorganization.
chemogenetics, NELC neurons, rMR pathway, liver regeneration, Th-Cre mice, AAV vectors, CNO administration, neural regulation, chronic stress, liver recovery, proliferation markers, Ki67, PCNA, liver regeneration inhibition, Chemical genetics
Learn about the AAV-BR1, AAV-BI30, AAV-X1 series, and rAAV-miniBEND systems for gene delivery, editing, and precise disease modeling in neurovascular research. These cutting-edge tools are paving the way for gene therapies in cerebrovascular diseases.
This study identifies a non-spinal bladder–brain vagal pathway that transmits inflammatory signals and maintains bladder homeostasis, revealed by viral tracing , DREADD-fMRI and Immunohistochemistry.
A comprehensive comparison of AAV and lentiviral vectors, covering gene delivery mechanisms, packaging capacity, immunogenicity, and in vivo vs in vitro applications, with case studies from gene therapy, neuroscience, and cancer research.
A Nature Communications study reveals a dual nose–brain axis in mice, showing how spoiled food odors activate distinct neural circuits to drive retching-like behavior and aversion.
Gut microbiota from bipolar disorder patients disrupts the VTA–mPFC dopamine pathway, impairing synaptic plasticity and inducing depression-like behaviors.
Discover the role of microglia in neurodegenerative diseases like Alzheimer's, Parkinson's, and ALS, and explore new therapeutic strategies targeting these cells.
This study reveals how tumor-derived SAM and METTL14-driven m⁶A modification rewire LPBN neural circuits to drive pain–depression comorbidity in PDAC.
A complete guide comparing GCaMP6, jGCaMP7, jGCaMP8 and RiboL1-jGCaMP8, covering sensitivity, kinetics, soma targeting and RO-injection brightness performance.