BC-0107 rAAV-EF1α-DIO-hChR2(H134R)-EYFP

Time:2024-12-31 11:26:24
BC-0107  rAAV-EF1α-DIO-hChR2(H134R)-EYFP
Features:Channelrhodopsins are light-gated ion channels that exist naturally in microalgae. hChR2 is a humanized version of ChR2 for mammalian expression. It is maximally excited by 470 nm light. The wild-type, as well as a few mutations, provide the fastest excitation of the channelrhodopsins offered, and are widely used in optogenetics techniques in neuroscience. Due to delayed channel closure, hChR2(H134R) is a gain-of-function mutation that produces larger photocurrents than wild-type hChR2, but slows down channel kinetics.

Gene/Insert name:hChR2(H134R)
Tag/Fusion protein:EYFP
Titer:>1x10^13 VG/mL,>2x10^12 VG/mL
Volume:100μL

References for using this product:
Cerebellar Purkinje cell firing promotes conscious recovery from anesthesia state through coordinating neuronal communications with motor cortex
Restoring the Function of Thalamocortical Circuit Through Correcting Thalamic Kv3.2 Channelopathy Normalizes Fear Extinction Impairments in a PTSD Mouse Model




 

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