Features:This AAV expresses ChETA-mCherry driven by a Dopamine receptor.
Promoter: D1 receptor promoter(Dopamine receptor promoter, specific expression in D1 receptor–positive neurons)
Channelrhodopsins are light-gated ion channels that exist naturally in microalgae. hChR2 is a humanized version of ChR2 for mammalian expression. It is maximally excited by 470 nm light. ChETA is a mutant of ChR2, combined with E123T and H134R mutations, has a faster dynamic change. ChETA allows neurons to emit a 200Hz spike when stimulated by a laser, while others ChR2 can only reach 40Hz.