Features:This AAV expresses ChETA-EGFP driven by a neuron hSyn promoter.
hSyn is a Human synapsin 1 gene promoter.
Channelrhodopsins are light-gated ion channels that exist naturally in microalgae. hChR2 is a humanized version of ChR2 for mammalian expression. It is maximally excited by 470 nm light. ChETA is a mutant of ChR2, combined with E123T and H134R mutations, has a faster dynamic change. ChETA allows neurons to emit a 200Hz spike when stimulated by a laser, while others ChR2 can only reach 40Hz.