Characteristics:ShRNA (short hairpin RNA) is a type of RNA molecule used in gene silencing techniques. It is designed to induce the RNA interference (RNAi) pathway, which leads to the degradation of specific mRNA molecules, thereby reducing or "knocking down" the expression of the target gene.
The mTH promoter is the Mouse Tyrosine Hydroxylase promoter, which can drive the expression of exogenous genes in dopaminergic neurons. The total length of this promoter is approximately 2500 bps. For more details, please refer to Addgene ID 99128.