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GRAB Neurotransmitter Fluorescent Probe- Brain Case

The neurotransmitter probe constructed based on the GPCR activation principle is named GRAB probe, a type of genetically encoded high spatiotemporal resolution neurotransmitter probe

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Calcium signal recording-Gels- Brain Case

Calcium signal recording technology detects the Ca2+ concentration in cells and converts it into fluorescence signals, transfers cell electrical activity into light signals. It uses genetically encoded calcium ion indicators GECIs, such as GCaMP.

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Chemical genetics-DREADDs-Brain Case

Chemical genetics, or pharmacogenetics, are non-invasive method of neural function manipulation. DREADDs technology refers to the activation or inhibition of DREADDs receptors by only the specific drug Clozapine-N-oxide (CNO).

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Optogenetics - BrainCase

Optogenetics combine optical and genetic means to precisely control the activity of specific neurons. Excitatory light-sensitive channels and inhibitory light-sensitive channels are commonly used.

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Gene Editing - CRSIPR cloning - BrainCase

CRISPR system is for gene editing. The sgRNA (small guide RNA) recognizes and binds to the target sequence guiding the Cas protein to cut at the binding site, resulting in a double-strand break (DSB) in the DNA, mediating CRISPR-Cas9 gene editing.

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RNA interference(RNAi)-siRNA-Brain Case

RNAi is highly efficient and specific inhibitor of gene expression, using viral vectors to mediate shRNA(short hairpin RNA) interference can regulate gene expression, and then study gene function

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Products and services

GRAB Neurotransmitter Fluorescent Probe- Brain Case

Calcium signal recording-Gels- Brain Case

Chemical genetics-DREADDs-Brain Case

Optogenetics - BrainCase

Gene Editing - CRSIPR cloning - BrainCase

RNA interference(RNAi)-siRNA-Brain Case

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