With a focus on advanced neuroscience, we provide advanced technology platforms to lead the innovation of viral tools for medical research.
Brain Case provides a variety of vector tools, including AAV, lentivirus, rabies virus, and herpes simplex virus, for gene regulation, gene editing, as well as in vitro and in vivo experiments.
Brain Case is a leading biotech company specializing in viral vectors for neural circuits, gene therapy, and tumor immunotherapy, with advanced GMP platforms.
Brain Case shares the scientific achievements of product users and provides practical techniques and tips.
Enjoy up to 35% OFF on viral vectors! Global delivery & fast turnaround from Brain Case Biotech. Promotion ends Nov 9, 2025.
Holiday research sale featuring AAVs, PRV/HSV/RV/VSV tools, combo packs, mystery boxes, and custom virus packaging discounts. Nov 24–Dec 7.
rAAV-miniBEND: Gene delivery to brain endothelial cells and modeling of vascular malformation diseases.
Explore the critical quality attributes (CQA) of AAV vectors, including identity, potency, purity, impurities, and safety, for safe and effective gene therapy.
A breakthrough red–green dual-sensor system enables high-resolution, minimally invasive in vivo imaging of L-lactate dynamics in awake mice, revealing metabolic–neuronal coupling.
R-eLACCO2.1 is a red fluorescent genetically encoded sensor enabling in vivo, cell-resolution imaging of extracellular L-lactate and neural activity in awake mice, fully compatible with GCaMP and FLIM.
A PNAS study reveals how linoleic acid and (Z)-9-tricosene, detected via the main olfactory system, interact with the VTA–mOT dopaminergic pathway to regulate rodent insect predation.
Learn how to solve AAV expression loss and weak fluorescence with step-by-step optimization of vector design, viral titer, injection dose, timing, detection, and sample processing.
On October 24, 2025, the team of Tongji University published “Engineered thoracic spinal cord organoids for transplantation after spinal cord injury”
These probes enable spectrally and spatially multiplexed imaging of extracellular and intracellular L-lactate in cultured cells (e.g., HeLa cells, neurons), brain slices, and live mice.
Optogenetic study shows H4R excites RVMM GABAergic neurons via TRPV1, suppressing sympathetic activity and lowering blood pressure.
New study reveals how impaired autophagy in OPCs accelerates brain aging and cognitive decline through CCL3/CCL5–CCR5 signaling. Brain Case offers full electrophysiology testing and analysis support.
It reveals the function of SVTg as a new brainstem reward center, which processes emotional value by integrating inputs from cortical and subcortical regions.