Features:It consists of ChEF/ChIEF, VChR1, VChR2 plus L171I mutation. Can be excited by orange-red light, which provides better membrane transport, higher photocurrent and faster kinetics compared to existing red-shifted ChRs. Transcranial optical activation of neurons in deep brain structures can be achieved without the need to surgically thin the skull, form a transcranial window or implant optical fibers.