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Gene Editing - CRSIPR cloning - BrainCase

CRISPR system is for gene editing. The sgRNA (small guide RNA) recognizes and binds to the target sequence guiding the Cas protein to cut at the binding site, resulting in a double-strand break (DSB) in the DNA, mediating CRISPR-Cas9 gene editing.

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RNA interference(RNAi)-siRNA-Brain Case

RNAi is highly efficient and specific inhibitor of gene expression, using viral vectors to mediate shRNA(short hairpin RNA) interference can regulate gene expression, and then study gene function

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